Moderate to Severe Plaque Psoriasis

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About Plaque Psoriasis

Psoriasis is a chronic inflammatory skin disease characterized by raised, red oval plaques on the skin with silvery scales. Lesions are typically painful or itchy and can be associated with a high degree of morbidity. Plaques on visible skin have a particular impact on physical, sexual, psychosocial, and even economic status; associated with reduced levels of employment and income. Psoriasis is more than a superficial disease, with 30% of patients having joint involvement, and a high correlation between psoriasis and obesity, diabetes, depression, metabolic syndrome, and cardiovascular risk.

About the Study

To assess the efficacy of an oral medication (NDI-034858) once a day at different doses for 12 weeks

Am I Eligible?

  • 18-70 years old
  • History of plaque psoriasis for at least 6 months
  • 10% body coverage area affected with psoriasis (10 “handprints” of area affected)
  • BMI range of 18-38
  • No immune-mediated conditions such as psoriatic arthritis, uveitis, or  inflammatory bowel disease, that requires systemic treatment
  • No evidence of erythrodermic, pustular, predominantly guttate psoriasis, drug-induced psoriasis

What Should I Expect?

  • Receive an oral medication with a 20% chance of receiving a placebo
  • 8 study visits; 12 weeks of treatment
  • Optional biopsies

Other Information 

  • Compensation may be available for time/travel 

If you are interested in participating in one of these studies, please provide your contact information below. If you are a qualified candidate, a representative from our research department will be in touch with you.

Volunteer for this study!

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